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Observational Study
. 2021 Jan 22;100(3):e24364.
doi: 10.1097/MD.0000000000024364.

Community ambulation in people with lower limb amputation: An observational cohort study

Affiliations
Observational Study

Community ambulation in people with lower limb amputation: An observational cohort study

Carlo Damiani et al. Medicine (Baltimore). .

Abstract

Lower limb amputation (LLA) is still a health issue requiring rehabilitation and long-term care even in industrial societies. Several studies on subjects with LLA have been focused on the efficacy of rehabilitation and factors influencing the use of prosthesis. However, literature data on the recovery of ability to walk outdoors, and thus to participate in social life in this population is limited.To investigate potential correlations between socio-demographic and clinical factors, and the use of the prosthesis for indoor and/or outdoor walking referred to as community ambulation (CA) in subjects with LLA.An observational cohort study on 687 LLA subjects was conducted. Socio-demographic and clinical characteristics of 302 subjects who received similar rehabilitative treatment with respect to the standard protocol were collected by a telephone survey with a structured questionnaire. The CA recovery, in terms of patient's autonomy and participation, assessed by Walking Handicap Scale, was considered as the main outcome.The univariate analysis demonstrated statistical significant positive correlation between CA and gender (χ2 = 3.901, P = .048); amputation level (χ2 = 24.657, P < .001); pre-LLA (χ2 = 6.338, P = .012) and current work activity (χ2 = 25.192, P < .001); prosthesis use (χ2 = 187.037, P < .01); and time from LLA (r = 0.183, P < .001); increasing age was negatively correlated with the outcome (r = -0.329, P < .001), while pain intensity was not significant. Being male (75.4%); trans-tibial (TT) amputation level (9.79%); working before (3.81%) and after LLA (7.68%); and the prosthesis use (24.63%) increased the probability of CA recovery. Multivariate binary logistic regression analysis confirmed that the prosthesis use (P < .001) and TT amputation level (P = .042) are predictors of a positive outcome (Walking Handicap Scale 4-6).These findings highlight the importance of the use of prosthesis in people with LLA for the restoration of a good capacity of participation (CA), especially in subjects with TT amputation level. The identification of predictive factors may help tailor-made rehabilitation approaches addressing an earlier reintegration to social life.

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Conflict of interest statement

The authors have no conflicts of interest to disclose.

Figures

Figure 1
Figure 1
Flowchart of the study procedure.
Figure 2
Figure 2
Effect of amputation level associated with the use of prosthesis on community ambulation.

References

    1. Willey J, Mentias A, Vaughan-Sarrazin M, et al. Epidemiology of lower extremity peripheral artery disease in veterans. J Vasc Surg 2018;68:527–35. - PMC - PubMed
    1. Jeffcoate W, Young B. Reducing amputation in diabetes: work from the West Country provides both evidence and a tool-kit. Diabetic Med 2018;35:8–9. - PubMed
    1. Moxey PW, Gogalniceanu P, Hinchliffe RJ, et al. Lower extremity amputations—a review of global variability in incidence. Diabetic Med 2011;28:1144–53. - PubMed
    1. Moxey PW, Hofman D, Hinchliffe RJ, et al. Epidemiological study of lower limb amputation in England between 2003 and 2008. Br J Surg 2010;97:1348–53. - PubMed
    1. Blumentritt S, Schmalz T, Jarasch R. Significance of static prosthesis alignment for standing and walking of patients with lower limb amputation. Der Orthopade 2001;30:161–8. - PubMed

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