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Comment
. 2021 Apr;18(4):217-218.
doi: 10.1038/s41575-021-00425-5. Epub 2021 Feb 5.

IBD risk prediction using multi-ethnic polygenic risk scores

Ashwin N Ananthakrishnan  1   2
Affiliations
Comment

IBD risk prediction using multi-ethnic polygenic risk scores

Ashwin N Ananthakrishnan. Nat Rev Gastroenterol Hepatol. 2021 Apr.
No abstract available

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Comment on

  • Common and Rare Variant Prediction and Penetrance of IBD in a Large, Multi-ethnic, Health System-based Biobank Cohort.
    Gettler K, Levantovsky R, Moscati A, Giri M, Wu Y, Hsu NY, Chuang LS, Sazonovs A, Venkateswaran S, Korie U, Chasteau C; UK IBD Genetics Consortium, National Institute of Diabetes, Digestive and Kidney Diseases Inflammatory Bowel Disease Genetics Consortium; Duerr RH, Silverberg MS, Snapper SB, Daly MJ, McGovern DP, Brant SR, Rioux JD, Kugathasan S, Anderson CA, Itan Y, Cho JH. Gettler K, et al. Gastroenterology. 2021 Apr;160(5):1546-1557. doi: 10.1053/j.gastro.2020.12.034. Epub 2020 Dec 24. Gastroenterology. 2021. PMID: 33359885 Free PMC article.

References

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    1. Beaudoin, M., Goyette, P. & Boucher, G. et al. Deep resequencing of GWAS loci identifies rare variants in CARD9, IL23R and RNF186 that are associated with ulcerative colitis. PLoS Genet. 9, e1003723 (2013). - DOI
    1. Rivas, M. A., Graham, D. & Sulem, P. et al. A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis. Nat. Commun. 7, 12342 (2016). - DOI

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