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Clinical Trial
. 1988 Feb;43(2):100-3.

A single dose epidural technique for caesarean section. A comparison between 0.5% bupivacaine plain and 0.5% bupivacaine with adrenaline

Affiliations
  • PMID: 3354801
Free article
Clinical Trial

A single dose epidural technique for caesarean section. A comparison between 0.5% bupivacaine plain and 0.5% bupivacaine with adrenaline

R S Laishley et al. Anaesthesia. 1988 Feb.
Free article

Abstract

An epidural technique based on a fractionated injection through a Tuohy needle of 20 ml over 10 minutes, was investigated in 40 mothers who underwent elective caesarean section. Mothers were randomized to receive either 0.5% bupivacaine plain or 0.5% bupivacaine with adrenaline 1:200,000. After a 2-ml test dose, the remaining 18 ml was injected over 5 minutes. The use of adrenaline did not significantly alter the onset or duration, but improved the efficacy of the epidural block. Mean time to onset of adequate surgical anaesthesia was 20 minutes. Only 10 patients required more than the initial 100 mg of bupivacaine. Epidural anaesthesia was supplemented in eight patients with nitrous oxide and/or intravenous opioids.

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