[Research Progress on Estimation of Postmortem Interval Using mRNA and ncRNA]
- PMID: 33550730
- DOI: 10.12116/j.issn.1004-5619.2020.06.011
[Research Progress on Estimation of Postmortem Interval Using mRNA and ncRNA]
Abstract
Postmortem interval （PMI） estimation has always been an important and difficult issue in the field of forensic pathology. In recent years, research progress on the estimation of PMI using RNA specific variation patterns after death has been made by researchers at home and aboard. This paper summarizes the specific application methods of messenger RNA and non-coding RNA for PMI estimation based on the literatures and discusses the existing problems and development trends, in order to provide technical reference for related studies and estimation practice.
题目: mRNA和ncRNA在死亡时间推断中的研究进展.
摘要: 死亡时间（postmortem interval，PMI）推断一直是法医病理学研究的重点和难点。近年来，国内外学者运用死后体内核糖核酸（ribonucleic acid，RNA）特异性变化规律推断PMI取得了一定研究进展。本文结合文献，综述了运用信使RNA（messenger RNA，mRNA）和非编码RNA（non-coding RNA，ncRNA）进行PMI推断的具体应用方法，并探讨了存在的问题及发展趋势，以期为相关研究和鉴定实践提供技术参考。.
关键词: 法医病理学；死亡时间推断；信使RNA；非编码RNA；综述.
Keywords: forensic pathology; estimation of postmortem interval; messenger RNA （mRNA）; non-coding RNA （ncRNA）; review.
Copyright© by the Editorial Department of Journal of Forensic Medicine.
Conflict of interest statement
The authors of this article and the planning committee members and staff have no relevant financial relationships with commercial interests to disclose.
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