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Review
. 2021 Aug;29(8):667-685.
doi: 10.1016/j.tim.2021.01.003. Epub 2021 Feb 4.

Shaping the Future of Probiotics and Prebiotics

Marla Cunningham  1 , M Andrea Azcarate-Peril  2 , Alan Barnard  3 , Valerie Benoit  4 , Roberta Grimaldi  5 , Denis Guyonnet  6 , Hannah D Holscher  7 , Kirsty Hunter  8 , Sarmauli Manurung  9 , David Obis  10 , Mariya I Petrova  11 , Robert E Steinert  12 , Kelly S Swanson  13 , Douwe van Sinderen  14 , Jelena Vulevic  15 , Glenn R Gibson  16
Affiliations
Free article
Review

Shaping the Future of Probiotics and Prebiotics

Marla Cunningham et al. Trends Microbiol. 2021 Aug.
Free article

Abstract

Recent and ongoing developments in microbiome science are enabling new frontiers of research for probiotics and prebiotics. Novel types, mechanisms, and applications currently under study have the potential to change scientific understanding as well as nutritional and healthcare applications of these interventions. The expansion of related fields of microbiome-targeted interventions, and an evolving landscape for implementation across regulatory, policy, prescriber, and consumer spheres, portends an era of significant change. In this review we examine recent, emerging, and anticipated trends in probiotic and prebiotic science, and create a vision for broad areas of developing influence in the field.

Keywords: future trends; microbiome; personalised; prebiotics; precision; probiotics.

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Conflict of interest statement

Declaration of Interests M.C., V.B., R.G., D.G., S.M., D.O., M.I.P., and R.E.S. are involved in research and development projects as employees of companies that produce, sell, and distribute food and/or healthcare products, including probiotics and prebiotics (M.C., Metagenics; V.B., General Mills; R.G., GSK Consumer Healthcare; D.G., Symrise Nutrition; S.M., Reckitt Benckiser; D.O., Danone Nutricia Research; M.I.P., Winclove Probiotics; R.E.S., DSM Nutritional Products). H.D.H has received grant funding from the Hass Avocado Board, the Almond Board of California, and the National Honey Board; presentation honoraria from Kellogg’s Company, PepsiCo, Nutricia North America, Tate & Lyle; and serves on the Grains Food Foundation scientific advisory board. M.A.A., A.B., K.H., K.S.S., D.S., J.V., and G.G. have no conflicts of interest to declare.

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