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. 2021;19(2):1773-1777.
doi: 10.1007/s10311-021-01187-x. Epub 2021 Feb 3.

SARS-CoV-2 is rapidly inactivated at high temperature

Jennifer Biryukov  1 , Jeremy A Boydston  1 , Rebecca A Dunning  1 , John J Yeager  1 , Stewart Wood  1 , Allison Ferris  1 , David Miller  1 , Wade Weaver  1 , Nathalie E Zeitouni  1 , Denise Freeburger  1 , Paul Dabisch  1 , Victoria Wahl  1 , Michael C Hevey  1 , Louis A Altamura  1
Affiliations

SARS-CoV-2 is rapidly inactivated at high temperature

Jennifer Biryukov et al. Environ Chem Lett. 2021.

Abstract

In the absence of a vaccine, preventing the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the primary means to reduce the impact of the 2019 coronavirus disease (COVID-19). Multiple studies have reported the presence of SARS-CoV-2 genetic material on surfaces suggesting that fomite transmission of SARS-CoV-2 is feasible. High temperature inactivation of virus has been previously suggested, but not shown. In the present study, we investigated the environmental stability of SARS-CoV-2 in a clinically relevant matrix dried onto stainless steel at a high temperature. The results show that at 54.5 °C, the virus half-life was 10.8 ± 3.0 min and the time for a 90% decrease in infectivity was 35.4 ± 9.0 min. These findings suggest that in instances where the environment can reach temperatures of at least 54.5 °C, such as in vehicle interior cabins when parked in warmer ambient air, that the potential for exposure to infectious virus on surfaces could be decreased substantially in under an hour.

Keywords: COVID-19; Coronavirus; Environmental decay; Heat; SARS-CoV-2; Viral inactivation.

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Conflict of interest statement

Conflicts of interestThe authors declare no conflict of interest. DHS S & T staff performed a review of this manuscript prior to submission and provided editorial feedback.

Figures

Fig. 1
Fig. 1
Impact of temperature on the surface decay of the the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
See this image and copyright information in PMC

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