Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Feb 1;17(1):23-28.
doi: 10.1002/cld.1045. eCollection 2021 Jan.

Nonalcoholic Fatty Liver Disease and Recent Guideline Updates

Affiliations
Review

Nonalcoholic Fatty Liver Disease and Recent Guideline Updates

Yumi Ando et al. Clin Liver Dis (Hoboken). .

Abstract

Watch a video presentation of this article.

PubMed Disclaimer

Figures

FIG 1
FIG 1
Proposed diagnostic and risk stratification algorithm for patients with suspected NAFLD. 1HBV and HCV serological workup should be completed in the primary care setting, with subsequent workup tailored to the individual patient by hepatology. Note that NAFLD may coexist with other chronic liver diseases. 2Evidence‐based optimal follow‐up of patients with NAFLD has not been established. The EASL recommends monitoring low‐risk patients with NAFLD without worsening metabolic risk factors every 2 to 3 years. 3Biopsy should also be considered in patients with increasing number of metabolic diseases who are at high risk for steatohepatitis.

References

    1. Wong RJ, Aguilar M, Cheung R, et al. Nonalcoholic steatohepatitis is the second leading etiology of liver disease among adults awaiting liver transplantation in the United States. Gastroenterology 2015;148:547‐555. - PubMed
    1. Chalasani N, Younossi Z, Lavine JE, et al. The diagnosis and management of non‐alcoholic fatty liver disease: practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association. Hepatology 2012;55:2005‐2023. - PubMed
    1. Chalasani N, Younossi Z, Lavine JE, et al. The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases. Hepatology 2018;67:328‐357. - PubMed
    1. Targher G, Byrne CD, Lonardo A, et al. Non‐alcoholic fatty liver disease and risk of incident cardiovascular disease: a meta‐analysis. J Hepatol 2016;65:589‐600. - PubMed
    1. Wong RJ, Tran T, Kaufman H, et al. Increasing metabolic co‐morbidities are associated with higher risk of advanced fibrosis in nonalcoholic steatohepatitis. PLoS One 2019;14:e0220612. - PMC - PubMed