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. 2021 Mar 4;57(18):2245-2248.
doi: 10.1039/d0cc08219h. Epub 2021 Feb 8.

Two-photon excited peptide nanodrugs for precise photodynamic therapy

Hongqian Cao  1 , Yanfei Qi, Xibao Gao, Zi Jin Wei, Jiarui Xia, Lei Wang, Hao Wang, Yang Yang, Junbai Li
Affiliations

Two-photon excited peptide nanodrugs for precise photodynamic therapy

Hongqian Cao et al. Chem Commun (Camb). .

Abstract

A novel peptide nanodrug composed of three functional motifs, bis(pyrene), FFVLK and CREKA, was used as a two-photon excited photosensitizer for precise photodynamic therapy (PDT). The system presented excellent two-photon imaging ability, tumor target effect and high reactive oxygen species productivity for improving treatment precision and efficiency in PDT.

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