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. 2020 Nov 19;59(2):e45-e48.
doi: 10.1515/cclm-2020-1338.

Parallel testing of 241 clinical nasopharyngeal swabs for the detection of SARS-CoV-2 virus on the Cepheid Xpert Xpress SARS-CoV-2 and the Roche cobas SARS-CoV-2 assays

Jason Wei Ming Tham  1 , Shu Chi Ng  1 , Chean Nee Chai  1 , Siyu Png  1 , Eunice Jia Min Tan  1 , Li Jie Ng  1 , Rui Ping Chua  1 , Musa Sani  1 , Donald Chiang  1 , Ker Xin Tan  1 , Nancy Wen Sim Tee  1 , Roland Jureen  1 , Shaun S Tan  1 , Gabriel Yan  2 , Benedict Yan  1   3 , Chun Kiat Lee  1
Affiliations
Free article

Parallel testing of 241 clinical nasopharyngeal swabs for the detection of SARS-CoV-2 virus on the Cepheid Xpert Xpress SARS-CoV-2 and the Roche cobas SARS-CoV-2 assays

Jason Wei Ming Tham et al. Clin Chem Lab Med. .
Free article
No abstract available

Keywords: COVID-19; GeneXpert; SARS-CoV-2; cobas; coronavirus; pandemic.

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References

    1. World Health Organization. Coronavirus disease (COVID-19) pandemic; 2020. Available from: https://www.who.int/emergencies/diseases/novel-coronavirus-2019 [Accessed 19 Aug 2020].
    1. Zhen, W, Manji, R, Smith, E, Berry, GJ. Comparison of four molecular in vitro diagnostic assays for the detection of SARS-CoV-2 in nasopharyngeal specimens. J Clin Microbiol 2020;58:e00743–20, https://doi.org/10.1128/jcm.00743-20.
    1. Lowe, CF, Matic, N, Ritchie, G, Lawson, T, Stefanovic, A, Champagne, S, et al.. Detection of low levels of SARS-CoV-2 RNA from nasopharyngeal swabs using three commercial molecular assays. J Clin Virol 2020;128:104387, https://doi.org/10.1016/j.jcv.2020.104387.
    1. Smithgall, MC, Scherberkova, I, Whittier, S, Green, DA. Comparison of Cepheid Xpert Xpress and Abbott ID Now to Roche cobas for the rapid detection of SARS-CoV-2. J Clin Virol 2020;128:104428, https://doi.org/10.1016/j.jcv.2020.104428.
    1. Broder, K, Babiker, A, Myers, C, White, T, Jones, H, Cardella, J, et al.. Test agreement between Roche Cobas 6800 and Cepheid GeneXpert Xpress SARS-CoV-2 assays at high cycle threshold ranges. J Clin Microbiol 2020;58:e01187–2, https://doi.org/10.1128/jcm.01187-20.

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