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Review
. 2021 Mar 22;22(4):397-405.
doi: 10.1093/ehjci/jeaa351.

Cardiac computed tomography in cardio-oncology: an update on recent clinical applications

Stefania Rosmini  1 , Ankita Aggarwal  2 , Daniel H Chen  1   3   4 , John Conibear  5 , Ceri L Davies  1 , Amit Kumar Dey  6   7 , Paula Edwards  8 , Avirup Guha  9 , Arjun K Ghosh  1   3   4
Affiliations
Review

Cardiac computed tomography in cardio-oncology: an update on recent clinical applications

Stefania Rosmini et al. Eur Heart J Cardiovasc Imaging. .

Abstract

Chemotherapy and radiotherapy have drastically improved cancer survival, but they can result in significant short- and long-term cardiovascular complications, most commonly heart failure from chemotherapy, whilst radiotherapy increases the risk of premature coronary artery disease (CAD), valve, and pericardial diseases. Cardiac computed tomography (CT) with calcium scoring has a role in screening asymptomatic patients for premature CAD, cardiac CT angiography (CTCA) allows the identification of significant CAD, also in the acute settings where concerns exist towards invasive angiography. CTCA integrates the diagnostic work-up and guides surgical/percutaneous management of valvular heart diseases and allows the assessment of pericardial conditions, including detection of effusion and pericardial calcification. It is a widely available and fast imaging modality that allows a one-step evaluation of CAD, myocardial, valvular, and pericardial disease. This review aims to provide an update on its current use and accompanying evidence-base for cardiac CT in the management of cardio-oncology patients.

Keywords: cardiac CT; cardio-oncology; coronary artery disease; pericardial disease; valvular disease.

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Figures

Figure 1
Figure 1
Different roles of Cardiac CT in screening, diagnosis, and management in cancer patients.
Figure 2
Figure 2
Coronary, valvular, and pericardial disease in Hodgkin lymphoma survivor treated with chemo and radiotherapy.
Figure 3
Figure 3
Radiation-induced valvular heart disease.
Figure 4
Figure 4
Chemotherapy-induced pericardial disease.
See this image and copyright information in PMC

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