Myosin heavy chain composition of single fibres from normal human muscle
- PMID: 3355518
- PMCID: PMC1148850
- DOI: 10.1042/bj2500307
Myosin heavy chain composition of single fibres from normal human muscle
Abstract
Electrophoretic analysis in the presence of 33% glycerol of purified myosin from normal human muscle shows three distinct protein bands which are identified as type 1, 2B, and 2A myosin heavy chain (MHC) isoforms by affinity-purified polyclonal antibodies. Analysis of MHC of single human muscle fibres shows that human muscles contain a large population of fibres showing the coexistence of type 2A and 2B MHC.
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