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. 1988 Mar;57(3):317-8.
doi: 10.1038/bjc.1988.70.

Oral urea in the treatment of secondary tumours in the liver

P I Clark  1 , M L Slevin, J A Webb, R J Osborne, S Jones, P F Wrigley
Affiliations
Free PMC article

Oral urea in the treatment of secondary tumours in the liver

P I Clark et al. Br J Cancer. 1988 Mar.
Free PMC article

Abstract

Twenty patients with secondary liver tumours, predominantly from colorectal carcinoma, were treated with oral urea at a daily dose of 8 gm-2. Treatment was well tolerated without side-effects. No objective responses were seen. It is concluded that oral urea is ineffective in the treatment of liver metastases from colorectal cancer.

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