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. 2021 Feb 8;21(1):83.
doi: 10.1186/s12888-020-03008-x.

Bipolar I disorder: a qualitative study of the viewpoints of the family members of patients on the nature of the disorder and pharmacological treatment non-adherence

Nasim Mousavi  1 , Marzieh Norozpour  2 , Zahra Taherifar  3 , Morteza Naserbakht  4 , Amir Shabani  4
Affiliations

Bipolar I disorder: a qualitative study of the viewpoints of the family members of patients on the nature of the disorder and pharmacological treatment non-adherence

Nasim Mousavi et al. BMC Psychiatry. .

Abstract

Background: Bipolar disorder is a common psychiatric disorder with a massive psychological and social burden. Research indicates that treatment adherence is not good in these patients. The families' knowledge about the disorder is fundamental for managing their patients' disorder. The purpose of the present study was to investigate the knowledge of the family members of a sample of Iranian patients with bipolar I disorder (BD-I) and to explore the potential reasons for treatment non-adherence.

Methods: This study was conducted by qualitative content analysis. In-depth interviews were held and open-coding inductive analysis was performed. A thematic content analysis was used for the qualitative data analysis.

Results: The viewpoints of the family members of the patients were categorized in five themes, including knowledge about the disorder, information about the medications, information about the treatment and the respective role of the family, reasons for pharmacological treatment non-adherence, and strategies applied by families to enhance treatment adherence in the patients. The research findings showed that the family members did not have enough information about the nature of BD-I, which they attributed to their lack of training on the disorder. The families did not know what caused the recurrence of the disorder and did not have sufficient knowledge about its prescribed medications and treatments. Also, most families did not know about the etiology of the disorder.

Conclusion: The lack of knowledge among the family members of patients with BD-I can have a significant impact on relapse and treatment non-adherence. These issues need to be further emphasized in the training of patients' families. The present findings can be used to re-design the guidelines and protocols in a way to improve treatment adherence and avoid the relapse of BD-I symptoms.

Keywords: Bipolar I disorder; Family psychological education; Qualitative study; Treatment non-adherence.

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Conflict of interest statement

The authors declare that they have no competing interests.

References

    1. Diagnostic and statistical manual of mental disorders. Fifth edition (DSM-5). Arlington: American Psychiatric Association; 2013.
    1. Kaushik P, Bhatia M. Burden and quality of life in spouses of patients with schizophrenia and bipolar disorder. Delhi Psychiatry J. 2013;16(1):83-9.
    1. Maji KR SMSRKS, Maji KR, Sood M, Sagar R, Khandelwal SK. No Title. 2012 Mar 18 [cited 2020 mar 16];58(2). Available from: http://www.ncbi.nlm.nih.gov/pubmed/21421638.
    1. Zergew A, Hailemariam D, Alem A, Kebede D. A longitudinal comparative analysis of economic and family caregiver burden due to bipolar disorder. Afr J Psychiatry. 2008;11(3):191–198. doi: 10.4314/ajpsy.v11i3.30268. - DOI - PubMed
    1. Shirkhoda SA. The investigation of the amount of cost for bipolar disorder type I and its related factors during the 1-year follow-up for the hospitalized patients in Iran educational-therapeutic psychiatric center [dissertaion]. Iran University of Medical Sciences ;2014.

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