Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2021 Jul;18(7):1624-1625.
doi: 10.1038/s41423-021-00645-4. Epub 2021 Feb 8.

A new predictive biomarker enables more accurate PD-1 blockade therapy

Kuojun Zhang  1 , Sheng Jiang  2
Affiliations
Comment

A new predictive biomarker enables more accurate PD-1 blockade therapy

Kuojun Zhang et al. Cell Mol Immunol. 2021 Jul.
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
A PD-1-mediated T cell exhaustion. B Restoration of antitumor T cell immunity with antibodies targeting PD-1. C Enhanced immunosuppressive function of Treg cells with antibodies targeting PD-1. mAb monoclonal antibody, MHC major histocompatibility complex, IFN-γ interferon gamma
See this image and copyright information in PMC

Comment on

References

    1. Kumagai S, et al. Nat. Immunol. 2020;21:1346–1358. doi: 10.1038/s41590-020-0769-3. - DOI - PubMed
    1. Ahmadzadeh M, et al. Blood. 2009;114:1537–1544. doi: 10.1182/blood-2008-12-195792. - DOI - PMC - PubMed
    1. Yokosuka T, et al. J. Exp. Med. 2012;209:1201–1217. doi: 10.1084/jem.20112741. - DOI - PMC - PubMed
    1. Hui E, et al. Science. 2017;355:1428–1433. doi: 10.1126/science.aaf1292. - DOI - PMC - PubMed
    1. Kansy BA, et al. Cancer Res. 2017;77:6353–6364. doi: 10.1158/0008-5472.CAN-16-3167. - DOI - PMC - PubMed

LinkOut - more resources