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Review
. 2021 Feb 8;36(6):e54.
doi: 10.3346/jkms.2021.36.e54.

What We Do Know and Do Not Yet Know about COVID-19 Vaccines as of the Beginning of the Year 2021

Jin Hong Yoo  1   2
Affiliations
Review

What We Do Know and Do Not Yet Know about COVID-19 Vaccines as of the Beginning of the Year 2021

Jin Hong Yoo. J Korean Med Sci. .

Abstract

Coronavirus disease 2019 (COVID-19), which started at the end of 2019 and has spread worldwide, has remained unabated in 2021. Since non-pharmaceutical interventions including social distancing are facing limitations in controlling COVID-19, additional absolute means to change the trend are necessary. To this end, coronavirus-specific antiviral drugs and vaccines are urgently needed, but for now, the priority is to promote herd immunity through extensive nationwide vaccination campaign. In addition to the vaccines based on the conventional technology such inactivated or killed virus or protein subunit vaccines, several vaccines on the new technological platforms, for example, nucleic acids-based vaccines delivered by viral carriers, nanoparticles, or plasmids as a medium were introduced in this pandemic. In addition to achieving sufficient herd immunity with vaccination, the development of antiviral treatments that work specifically against COVID-19 will also be necessary to terminate the epidemic completely.

Keywords: COVID-19; Herd Immunity; Vaccine.

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Conflict of interest statement

The author has no potential conflicts of interest to disclose.

References

    1. Yoo JH. Will the third wave of coronavirus disease 2019 really come in Korea? J Korean Med Sci. 2020;35(10):e110. - PMC - PubMed
    1. Yoo JH. Social distancing and lessons from Sweden's lenient strategy against corona virus disease 2019. J Korean Med Sci. 2020;35(27):e250. - PMC - PubMed
    1. Scavone C, Brusco S, Bertini M, Sportiello L, Rafaniello C, Zoccoli A, et al. Current pharmacological treatments for COVID-19: what's next? Br J Pharmacol. 2020;177(21):4813–4824. - PMC - PubMed
    1. Izda V, Jeffries MA, Sawalha AH. COVID-19: a review of therapeutic strategies and vaccine candidates. Clin Immunol. 2021;222:108634. - PMC - PubMed
    1. Beigel JH, Tomashek KM, Dodd LE, Mehta AK, Zingman BS, Kalil AC, et al. Remdesivir for the treatment of Covid-19 - final report. N Engl J Med. 2020;383(19):1813–1826. - PMC - PubMed

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