A Malignant Case of Arrested Development: Cancer Cell Dormancy Mimics Embryonic Diapause
- PMID: 33561394
- DOI: 10.1016/j.ccell.2021.01.013
A Malignant Case of Arrested Development: Cancer Cell Dormancy Mimics Embryonic Diapause
Abstract
Writing in Cancer Cell and Cell, two groups investigate the nature of dormant cancer cells that persist after chemotherapy. These cells adopt a state that resembles diapause, an evolutionarily conserved adaptation used by embryos to survive inhospitable conditions. Understanding cancer diapause could uncover therapeutic strategies that reduce cancer relapse.
Copyright © 2021 Elsevier Inc. All rights reserved.
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