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Comment
. 2021 Feb 8;39(2):148-150.
doi: 10.1016/j.ccell.2021.01.017.

Heterogeneity in Metastatic Potential of Cancer Cells Is Revealed En Masse

Pavitra Viswanath  1 , Alana L Welm  2
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Free article
Comment

Heterogeneity in Metastatic Potential of Cancer Cells Is Revealed En Masse

Pavitra Viswanath et al. Cancer Cell. .
Free article

Abstract

A new study in Nature determines metastatic tropism in xenograft mouse models. This results in a metastasis map for 21 tumor types, the utility of which is demonstrated by identifying lipid metabolism to be uniquely altered in breast cancer cell lines that metastasize to the brain.

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Conflict of interest statement

Declaration of Interests The authors declare no competing interests.

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  • A metastasis map of human cancer cell lines.
    Jin X, Demere Z, Nair K, Ali A, Ferraro GB, Natoli T, Deik A, Petronio L, Tang AA, Zhu C, Wang L, Rosenberg D, Mangena V, Roth J, Chung K, Jain RK, Clish CB, Vander Heiden MG, Golub TR. Jin X, et al. Nature. 2020 Dec;588(7837):331-336. doi: 10.1038/s41586-020-2969-2. Epub 2020 Dec 9. Nature. 2020. PMID: 33299191 Free PMC article.

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