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. 1988;47(1-2):84-5.
doi: 10.1159/000132512.

Evidence for in situ amplification of a germ line homogeneously staining region in the mouse

B Boldyreff  1 , H Winking, A Weith, W Traut
Affiliations

Evidence for in situ amplification of a germ line homogeneously staining region in the mouse

B Boldyreff et al. Cytogenet Cell Genet. 1988.

Abstract

A cloned DNA sequence that is specific for a germ line homogeneously staining region (HSR) on chromosome 1 of the mouse was found to be homologous to a single copy sequence in non-HSR mice. By in situ hybridization, the sequence in non-HSR mice was localized to approximately the same site as the insertion site of the HSR on chromosome 1 of HSR mice, indicating in situ amplification of the HSR.

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