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Case Reports
. 2021 Feb 9;14(2):e240022.
doi: 10.1136/bcr-2020-240022.

Spontaneous coronary artery dissection in association with cabergoline therapy

Affiliations
Case Reports

Spontaneous coronary artery dissection in association with cabergoline therapy

Zia Saleh et al. BMJ Case Rep. .

Abstract

Spontaneous coronary artery dissection (SCAD) is a rare but increasingly recognised cause of acute coronary syndrome. While numerous risk factors are associated with SCAD, one potential cause is coronary artery vasospasm. The use of cabergoline-an ergot derivative and dopamine agonist that may induce vasospasm-has been associated with SCAD in one other case report worldwide. Here, we describe SCAD in a 37-year-old woman on long-term cabergoline therapy with no other cardiac risk factors. Cabergoline-induced SCAD should be considered in patients presenting with an acute coronary syndrome who are treated with this medication.

Keywords: cardiovascular medicine; drugs: endocrine system.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
ECGs demonstrating baseline (top), preangiogram hyperacute T-waves (middle) and postangiogram (bottom) ST changes and T-wave inversions.

References

    1. Mehta NK, Malkani S, Ockene I. Spontaneous coronary artery dissection during cabergoline therapy. Tex Heart Inst J 2012;39:92–4. - PMC - PubMed
    1. Heart and Stroke Foundation of Canada Spontaneous coronary artery dissection [Internet]. Heart and Stroke Foundation of Canada, 2020. Available: https://www.heartandstroke.ca/heart/conditions/spontaneous-coronary-arte...
    1. Hayes SN, Kim ESH, Saw JWL. Spontaneous coronary artery dissection: current state of the science. Circulation 2018;137:e523–57. - PMC - PubMed
    1. Thygesen K, Alpert JS, Jaffe AS, et al. . Fourth universal definition of myocardial infarction (2018). J Am Coll Cardiol 2018;72:2231–64. 10.1016/j.jacc.2018.08.1038 - DOI - PubMed
    1. JWL S, Hassan S S, et al. . Outcomes of percutaneous coronary artery intervention in patients with non-atherosclerotic spontaneous coronary artery dissection. J Am Coll Cardiol 2018;7:A6.

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