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Case Reports
. 2021 Feb 9;14(2):e241403.
doi: 10.1136/bcr-2020-241403.

Monocular syphilitic uveitis

Deirdre A Harford  1 , Kit Green Sanderson  2 , Kirk A J Stephenson  3 , Conor C Murphy  1   2
Affiliations
Case Reports

Monocular syphilitic uveitis

Deirdre A Harford et al. BMJ Case Rep. .
No abstract available

Keywords: drugs: infectious diseases; eye; headache (including migraines); retina; syphilis.

PubMed Disclaimer

Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
(A) Widefield colour photograph of the left fundus showing two clusters of central vitritis with wedge-shaped temporal area of abnormality surrounded by intraretinal white dots. (B) Late phase wide-field FFA of the left fundus showing nasal retinal vasculitis with a well-circumscribed temporal wedge-shaped area of hyperfluorescence; note, the intraretinal white dots are not uniformly apparent on FFA. (C) OCT image showing normal retinal structure with obscuration by vitritis artefact. FFA, fundus fluorescein angiography; OCT, optical coherence tomography.
Figure 2
Figure 2
(A) Widefield fundus photograph of the left fundus 4 weeks after systemic antimicrobial treatment with dramatic improvement in vitritis, resolution of ‘active’ intraretinal white dots and development of fine round intraretinal pigmentation, indicative of resolved inflammation. (B) Widefield autofluorescence image showing a large temporal wedge of mottled hyperautofluorescence which is larger than the original clinically apparent extent of retinitis. (C) Optical coherence tomography showing preserved foveal outer retinal architecture, absence of macular oedema and clearing vitreous artefact.
See this image and copyright information in PMC

References

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    1. Bertrand P-J, Jamilloux Y, Ecochard R, et al. . Uveitis: Autoimmunity… and beyond. Autoimmun Rev 2019;18:102351. 10.1016/j.autrev.2019.102351 - DOI - PubMed
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    1. Shalaby IA, Dunn JP, Semba RD, et al. . Syphilitic uveitis in human immunodeficiency virus-infected patients. Arch Ophthalmol 1997;115:469–73. 10.1001/archopht.1997.01100150471003 - DOI - PubMed
    1. CDC Clinical Advisory Ocular syphilis in the United States. Available: https://www.cdc.gov/std/syphilis/clinicaladvisoryos2015.htm [Accessed 07 Dec 2020].

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