Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2021 Nov-Dec;23(6):600-601.
doi: 10.4103/aja.aja_2_21.

The use of spermatogonial stem cells to correct a mutation causing meiotic arrest

Qijing Lei  1 , Geert Hamer  1
Affiliations
Comment

The use of spermatogonial stem cells to correct a mutation causing meiotic arrest

Qijing Lei et al. Asian J Androl. 2021 Nov-Dec.
No abstract available

PubMed Disclaimer

Conflict of interest statement

None

Comment on

References

    1. Jan SZ, Jongejan A, Korver CM, van Daalen SK, van Pelt AM, et al. Distinct prophase arrest mechanisms in human male meiosis. Development. 2018;145:dev160614. - PMC - PubMed
    1. Enguita-Marruedo A, Sleddens-Linkels E, Ooms M, de Geus V, Wilke M, et al. Meiotic arrest occurs most frequently at metaphase and is often incomplete in azoospermic men. Fertil Steril. 2019;112:1059–70.e3. - PubMed
    1. Wang YH, Yan M, Zhang X, Liu XY, Ding YF, et al. Rescue of male infertility through correcting a genetic mutation causing meiotic arrest in spermatogonial stem cells. Asian J Androl. 2021 Doi: 10.4103/aja.aja_97_20. [Epub ahead of print] - PMC - PubMed
    1. Mulder CL, Zheng Y, Jan SZ, Struijk RB, Repping S, et al. Spermatogonial stem cell autotransplantation and germline genomic editing: a future cure for spermatogenic failure and prevention of transmission of genomic diseases. Hum Reprod Update. 2016;22:561–73. - PMC - PubMed
    1. Wu Y, Zhou H, Fan X, Zhang Y, Zhang M, et al. Correction of a genetic disease by CRISPR-Cas9-mediated gene editing in mouse spermatogonial stem cells. Cell Res. 2015;25:67–79. - PMC - PubMed