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. 2021 Mar 1;40(3):251-254.
doi: 10.1097/INF.0000000000003027.

Breakthrough Candidemia in Pediatric Patients With Cancer From a Brazilian Center

Anna Carlota Mott Barrientos  1 , João Nobrega de Almeida Junior  2   3 , Nadia Litvinov  1 , Vera Bain  1 , Lilian Maria Cristofani  1 , Maria Fernanda Badue Pereira  1 , Camila Sanson Yoshino de Paula  1 , Adriana Lopes Motta  2 , Flavia Rossi  2 , Gilda Maria Bárbaro Del Negro  3 , Danilo Yamamoto Thomaz  3 , Heloisa Helena Sousa Marques  1
Affiliations

Breakthrough Candidemia in Pediatric Patients With Cancer From a Brazilian Center

Anna Carlota Mott Barrientos et al. Pediatr Infect Dis J. .

Abstract

We analyzed 19 cases of breakthrough candidemia from a referral pediatric cancer center in Brazil. All patients had neutropenia and were under antifungal prophylactic regimens, mostly micafungin (68%). Most of the patients were treated with amphotericin B formulations and 30-day mortality was 21%. Candida parapsilosis was the main etiologic agent (63%), and horizontal transmission was not evidenced by microsatellite analysis.

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Conflict of interest statement

The authors have no conflicts of interest to disclose.

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