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. 2021 Jul 3;17(7):2197-2204.
doi: 10.1080/21645515.2020.1857201. Epub 2021 Feb 10.

Meningococcal vaccines in China

Yinghua Xu  1 , Yanan Li  1 , Shanshan Wang  1 , Maoguang Li  1 , Miao Xu  1 , Qiang Ye  1
Affiliations

Meningococcal vaccines in China

Yinghua Xu et al. Hum Vaccin Immunother. .

Abstract

Meningococcal meningitis caused by Neisseria meningitidis is a reportable infectious disease in China, due to the high incidence of meningitis in the era before the availability of vaccines. The disease incidence was markedly reduced after meningococcal vaccination was introduced in the 1980s. Currently, there are polysaccharide, conjugate, and combined vaccine formulations against meningococcal meningitis in the Chinese market, almost all of which are produced by domestic manufacturers. It is necessary to further enhance national meningococcal surveillance to improve the level of prevention and control of meningococcus. However, the immune efficacy and persistence of immunity of vaccines should be monitored. More importantly, additional investments should be made to develop serogroup B meningococcal vaccines.

Keywords: China; Neisseria meningitidis; conjugate vaccines; invasive meningococcal disease; polysaccharides vaccines; quality control.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Figure 1.
Figure 1.
Reported meningococcal meningitis and death cases in China, 2002–2019
Figure 2.
Figure 2.
Number of lot release of different types of meningococcal vaccines in China, 2010–2019
See this image and copyright information in PMC

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