Microbial memories
- PMID: 33567260
- DOI: 10.1016/j.immuni.2021.01.009
Microbial memories
Abstract
The microbiota impedes pathogen invasion of the intestinal ecosystem, a phenomenon termed colonization resistance. In an upcoming issue of Cell, Stacy et al. describe host-initiated metabolite pathways that functionally alter the microbiota after primary infection, thereby augmenting colonization resistance to subsequent infection.
Copyright © 2021 Elsevier Inc. All rights reserved.
Comment on
-
Infection trains the host for microbiota-enhanced resistance to pathogens.Cell. 2021 Feb 4;184(3):615-627.e17. doi: 10.1016/j.cell.2020.12.011. Epub 2021 Jan 15. Cell. 2021. PMID: 33453153 Free PMC article.
Similar articles
-
The Roles of Inflammation, Nutrient Availability and the Commensal Microbiota in Enteric Pathogen Infection.Microbiol Spectr. 2015 Jun;3(3). doi: 10.1128/microbiolspec.MBP-0008-2014. Microbiol Spectr. 2015. PMID: 26185088
-
Antibiotic-Driven Dysbiosis Mediates Intraluminal Agglutination and Alternative Segregation of Enterococcus faecium from the Intestinal Epithelium.mBio. 2015 Nov 10;6(6):e01346-15. doi: 10.1128/mBio.01346-15. mBio. 2015. PMID: 26556272 Free PMC article.
-
Colonization resistance and microbial ecophysiology: using gnotobiotic mouse models and single-cell technology to explore the intestinal jungle.FEMS Microbiol Rev. 2013 Sep;37(5):793-829. doi: 10.1111/1574-6976.12024. Epub 2013 Jun 5. FEMS Microbiol Rev. 2013. PMID: 23662775 Review.
-
Early life microbial colonization of the gut and intestinal development differ between genetically divergent broiler lines.BMC Genomics. 2015 May 28;16(1):418. doi: 10.1186/s12864-015-1646-6. BMC Genomics. 2015. PMID: 26017153 Free PMC article.
-
Intestinal colonization: how key microbial players become established in this dynamic process: microbial metabolic activities and the interplay between the host and microbes.Bioessays. 2013 Oct;35(10):913-23. doi: 10.1002/bies.201300073. Epub 2013 Aug 15. Bioessays. 2013. PMID: 23946088 Review.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources