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. 2021 Feb 8;10(4):639.
doi: 10.3390/jcm10040639.

Long-Term Technical Performance of the Osypka QT-5® Ventricular Pacemaker Lead

Georg Semmler  1   2 , Fabian Barbieri  3 , Karin Thudt  1 , Paul Vock  1 , Deddo Mörtl  1 , Harald Mayr  1 , Christian Georg Wollmann  1 , Agne Adukauskaite  3 , Bernhard Pfeifer  4   5 , Thomas Senoner  3 , Wolfgang Dichtl  3
Affiliations

Long-Term Technical Performance of the Osypka QT-5® Ventricular Pacemaker Lead

Georg Semmler et al. J Clin Med. .

Abstract

Background: Lead-associated complications and technical issues in patients with cardiac implantable electronic devices are common but underreported in the literature.

Methods: All patients undergoing implantation of the Osypka QT-5® ventricular lead at the University Clinic St. Pölten between 1 January 2006 and 31 December 2012 were retrospectively analyzed (n = 211). Clinical data including pacemaker follow-up examinations and the need for lead revisions were assessed. Kaplan-Meier analysis to estimate the rate of lead dysfunction during long-term follow-up was conducted.

Results: Patients were followed for a median of 5.2 years (interquartile range (IQR) 2.0-8.7). R-wave sensing properties at implantation, compared to last follow-up, remained basically unchanged: 9.9 mV (IQR 6.8-13.4) and 9.6 mV (IQR 5.6-12.0), respectively). Ventricular pacing threshold significantly increased between implantation (0.5 V at 0.4 ms; IQR 0.5-0.8) and the first follow-up visit (1.0 V at 0.4 ms; IQR 0.8-1.3; p < 0.001) and this increase persisted throughout to the last check-up (0.9 V at 0.4 ms; IQR 0.8-1.2). Impedance significantly declined from 1142 Ω (IQR 955-1285) at implantation to 814 Ω (IQR 701-949; p < 0.001) at the first check-up, followed by a further decrease to 450 Ω (IQR 289-652; p < 0.001) at the last check-up. Overall, the Osypka QT-5® ventricular lead was replaced in 36 patients (17.1%).

Conclusions: This report shows an unexpected high rate of technical issues of the Osypka QT-5® ventricular lead during long-term follow-up.

Keywords: impedance decline; lead replacement; pacemaker malfunction; reoperation.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Device characteristics (lead impedance, sensing and pacing threshold) at implantation and at last follow-up: (A) differences in ventricular lead impedance at implantation and at last follow-up; (B) differences in ventricular sensing at implantation and at last follow-up; (C) differences in ventricular pacing threshold at implantation and at last follow-up. Whiskers in box plots mark the 95% (2.5–97.5%) confidence interval.
Figure 2
Figure 2
Kaplan-Meier curve describing the prevalence of dysfunction of the Osypka QT-5® ventricular lead.
See this image and copyright information in PMC

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