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. 1988 Mar;26(3):429-32.
doi: 10.1128/jcm.26.3.429-432.1988.

Risk factors for candidemia in cancer patients: a case-control study

A Karabinis  1 , C Hill, B Leclercq, C Tancrède, D Baume, A Andremont
Affiliations

Risk factors for candidemia in cancer patients: a case-control study

A Karabinis et al. J Clin Microbiol. 1988 Mar.

Abstract

Risk factors for candidemia were analyzed in a case-control study of 30 cancer patients with candidemia and 58 controls. In a univariate analysis, previous surgery, neutropenia, central catheterization, chemotherapy, specific antibiotic treatments, and peripheral cultures positive for Candida spp. were associated with a significantly increased risk of candidemia. In a multivariate logistic model, the significant risk factors for candidemia were positive peripheral cultures for Candida spp. (P = 0.02), central catheterization (P = 0.03), and neutropenia (P = 0.05). These results should help to identify cancer patients with a high risk of candidemia, who should be given early systemic antifungal therapy.

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