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Comment
. 2021 Feb 10;29(2):152-154.
doi: 10.1016/j.chom.2021.01.008.

Giant DNA viruses make big strides in eukaryote evolution

Shifeng Cheng  1 , Gane Ka-Shu Wong  2 , Michael Melkonian  3
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Giant DNA viruses make big strides in eukaryote evolution

Shifeng Cheng et al. Cell Host Microbe. .
Free article

Abstract

Nucleocytoplasmic large DNA viruses (NCLDVs) are widespread in the biosphere. This issue of Cell Host & Microbe, Nelson et al., and a recent Nature paper, Moniruzzaman et al., show NCLDVs can integrate into host genomes, highlighting a mechanism of large-scale virus-mediated horizontal gene transfer (vHGT) driving eukaryotic evolution.

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