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Comment
. 2021 Feb 10;29(2):158-159.
doi: 10.1016/j.chom.2021.01.011.

Immunologic goalposts for TB vaccine development

Peter K Um  1 , William R Bishai  2
Affiliations
Comment

Immunologic goalposts for TB vaccine development

Peter K Um et al. Cell Host Microbe. .

Abstract

A limiting factor in identifying effective tuberculosis (TB) vaccines is our incomplete understanding of correlates of protection. In this issue of Cell Host & Microbe, Esaulova et al. reveal cell types associated with TB containment and disease progression in non-human primates, which may provide immunologic goalposts for vaccine design.

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Conflict of interest statement

Declaration of interests P.K.U. and W.R.B. are inventors on patents concerning recombinant BCG vaccines for TB.

Comment on

  • The immune landscape in tuberculosis reveals populations linked to disease and latency.
    Esaulova E, Das S, Singh DK, Choreño-Parra JA, Swain A, Arthur L, Rangel-Moreno J, Ahmed M, Singh B, Gupta A, Fernández-López LA, de la Luz Garcia-Hernandez M, Bucsan A, Moodley C, Mehra S, García-Latorre E, Zuniga J, Atkinson J, Kaushal D, Artyomov MN, Khader SA. Esaulova E, et al. Cell Host Microbe. 2021 Feb 10;29(2):165-178.e8. doi: 10.1016/j.chom.2020.11.013. Epub 2020 Dec 18. Cell Host Microbe. 2021. PMID: 33340449 Free PMC article.

References

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