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Comment
. 2021 Mar 15:283:262-264.
doi: 10.1016/j.jad.2021.01.046. Epub 2021 Jan 25.

Comments to Drs. Bahji, Vazquez, and Zarate

Wayne C Drevets  1 , Vanina Popova  2 , Ella J Daly  3 , Stephane Borentain  4 , Rosanne Lane  5 , M Soledad Cepeda  6 , Maju Mathews  4 , Husseini K Manji  7 , Carla M Canuso  7
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Comment

Comments to Drs. Bahji, Vazquez, and Zarate

Wayne C Drevets et al. J Affect Disord. .
Free article

Abstract

In the absence of head-to-head studies directly comparing the efficacy of intranasal esketamine to that of intravenous ketamine, valid conclusions regarding comparative efficacy cannot be made based on the existing data from trials using markedly differing study designs and patient populations.

Keywords: Depression; Esketamine; Ketamine; Major depressive disorder.

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