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Case Reports
. 2021 Feb 11;15(1):70.
doi: 10.1186/s13256-020-02549-9.

A 23-year-old man with acute lung injury after using a tetrahydrocannabinol-containing vaping device: a case report

Anthony Lucero  1 , Niklas Eriksson  2 , Carli Nichta  2 , Kimberly Sokol  2
Affiliations
Case Reports

A 23-year-old man with acute lung injury after using a tetrahydrocannabinol-containing vaping device: a case report

Anthony Lucero et al. J Med Case Rep. .

Abstract

Background: Vaping-associated lung injury is a newly emerging disease process with the potential for serious health implications and high mortality, even despite the lack of underlying lung disease. We present a case of a young, otherwise healthy patient with tetrahydrocannabinol vaping-associated lung injury.

Case presentation: A 23-year-old Caucasian man with a past history of tetrahydrocannabinol vaping and benzodiazepine and methamphetamine abuse presented to the emergency department of our institution with a complaint of "feeling malnourished" over the past 5 days, along with associated fevers, cough, and vomiting. His past medical, surgical, family, and social histories were significant only for the recent use of marijuana vaping pens. Upon initial presentation, the patient appeared to be in significant respiratory distress. A computed tomographic scan of his chest demonstrated diffuse central predominant interstitial opacities, and he was admitted to the medical intensive care unit, where he was eventually intubated for hypoxic respiratory failure. No other cause of his respiratory failure was found, and it was ultimately believed that the patient had sustained a vaping-associated lung injury.

Conclusion: Tetrahydrocannabinol-containing vaping-associated lung injury is still poorly understood overall and is currently being investigated by the Centers for Disease Control and Prevention. In the meantime, physicians should consider vaping to be a public health emergency. We summarize the appropriate history, physical examination, appropriate workup, and therapies that physicians should be aware of in order to appropriately manage and treat patients presenting with suspected vaping-associated lung injury.

Keywords: Case report; Lung injury; VALI; Vaping.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Historical and current timeline of clinical information
Fig. 2
Fig. 2
Chest x-ray demonstrating diffuse central predominant interstitial opacities (black arrows)
Fig. 3
Fig. 3
Axial view computed tomographic scan of the chest demonstrating diffuse central predominant interstitial opacities (black arrows)
Fig. 4
Fig. 4
Sagittal view computed tomographic scan further demonstrating diffuse central predominant interstitial opacities (black arrows)
See this image and copyright information in PMC

References

    1. Centers for Disease Control and Prevention. Outbreak of lung injury associated with the use of e-cigarette, or vaping, products. https://www.cdc.gov/tobacco/basic_information/e-cigarettes/severe-lung-d.... Accessed 4 Aug 2020.
    1. Perrine CG, Pickens CM, Boehmer TK, et al. Characteristics of a multistate outbreak of lung injury associated with e-cigarette use or vaping: United States. Morb Mortal Wkly Rep. 2019;68(39):860–864. doi: 10.15585/mmwr.mm6839e1. - DOI - PMC - PubMed
    1. Ghinai I, Pray IW, Navon L, et al. E-cigarette product use, or vaping, among persons with associated lung injury: Illinois and Wisconsin. Morb Mortal Wkly Rep. 2019;68(39):865–869. doi: 10.15585/mmwr.mm6839e2. - DOI - PMC - PubMed
    1. Lal A, Mishra AK, Sahu KK. Vitamin E acetate and e-cigarette or vaping product-associated lung injury (EVALI): an update. Am J Med. 2020;133(5):e204. doi: 10.1016/j.amjmed.2019.11.005. - DOI - PubMed
    1. Kaur G, Muthumalage T, Rahman I. Mechanisms of toxicity and biomarkers of flavoring and flavor enhancing chemicals in emerging tobacco and non-tobacco products. Toxicol Lett. 2018;288:143–155. doi: 10.1016/j.toxlet.2018.02.025. - DOI - PMC - PubMed

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