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Comment
. 2021 Feb;590(7846):376-377.
doi: 10.1038/d41586-021-00388-2.

Neanderthal-like 'mini-brains' created in lab with CRISPR

Ariana Remmel
Comment

Neanderthal-like 'mini-brains' created in lab with CRISPR

Ariana Remmel. Nature. 2021 Feb.
No abstract available

Keywords: Evolution; Stem cells.

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Comment on

  • Human Stem Cell Resources Are an Inroad to Neandertal DNA Functions.
    Dannemann M, He Z, Heide C, Vernot B, Sidow L, Kanton S, Weigert A, Treutlein B, Pääbo S, Kelso J, Camp JG. Dannemann M, et al. Stem Cell Reports. 2020 Jul 14;15(1):214-225. doi: 10.1016/j.stemcr.2020.05.018. Epub 2020 Jun 18. Stem Cell Reports. 2020. PMID: 32559457 Free PMC article.
  • Reintroduction of the archaic variant of NOVA1 in cortical organoids alters neurodevelopment.
    Trujillo CA, Rice ES, Schaefer NK, Chaim IA, Wheeler EC, Madrigal AA, Buchanan J, Preissl S, Wang A, Negraes PD, Szeto RA, Herai RH, Huseynov A, Ferraz MSA, Borges FS, Kihara AH, Byrne A, Marin M, Vollmers C, Brooks AN, Lautz JD, Semendeferi K, Shapiro B, Yeo GW, Smith SEP, Green RE, Muotri AR. Trujillo CA, et al. Science. 2021 Feb 12;371(6530):eaax2537. doi: 10.1126/science.aax2537. Science. 2021. PMID: 33574182 Free PMC article.

References

    1. Trujillo, C. A. et al. Science 371, eaax2537 (2021). - DOI - PubMed
    1. Dannemann, M. et al. Stem Cell Rep. 15, 214–225 (2020). - DOI