Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2020 Dec 28;34(2):148-150.
doi: 10.4103/1319-4534.305039. eCollection 2020 Apr-Jun.

Central retinal vein occlusion associated with the use of tranexamic acid

Ali M Al Shaharani  1 , Turki A Al Ghamdi  1
Affiliations
Case Reports

Central retinal vein occlusion associated with the use of tranexamic acid

Ali M Al Shaharani et al. Saudi J Ophthalmol. .

Abstract

Here we report a case of central retinal vein occlusion that developed after using tranexamic acid. A 46-year-old female not known to have any previous illness came to the ophthalmology clinic complaining of sudden blurring of the vision in her left eye for almost 1 month, for which it is advised that tranexamic acid should be discontinued.

Keywords: Anti-fibrinolytic; central retinal vein occlusion (CRVO); tranexamic acid (TA).

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
(a and b) Color fundus of the left eye showing flame-shaped hemorrhages in all four quadrants, disc swelling, venous tortuosity, retinal and macular edema, but no neovascularization of the disc or elsewhere
Figure 2
Figure 2
(a and b) After treatment color fundus photo of left eye; (c) optical coherence tomography showing normal appearance after treatment
See this image and copyright information in PMC

References

    1. Wellington K, Wagstaff AJ. Drugs. 2003;63:1417. https://doi.org/10.2165/00003495-200363130-00008. - PubMed
    1. Upadhyay SP, Mallick PN, Jagia M, Singh RKA. Acute arterial thrombosis associated with inadvertent high dose of tranexamic acid. Ind J Crit Care Med: Peer-Reviewed Off Publ Indian Soc Crit Care Med. 2013;17(4):237–9. https://doi.org/10.4103/0972-5229.118443. - PMC - PubMed
    1. Ramstrom G, Blomback M, Egberg N, Johnsson H, Ljungberg B, Schulman S. Oral surgery in patients with hereditary bleeding disorders.A survey of treatment in the Stockholm area (1974-1985) Int J Oral Maxillofac Surg. 1989;18:320–2. [PubMed] - PubMed
    1. Thrombosis with Tranexamic Acid for Menorrhagia Prescriber Update 24(2):26-27 October 2003 Dr Ruth Savage, Medical Assessor, New Zealand Pharmacovigilance Centre, Dunedin. <https://medsafe.govt.nz/profs/PUarticles/TXAclot.htm> .
    1. A drug-induced central retinal vein occlusion A BAUDOT F TRECHOT B BATTA K ANGIOI First published: 06 August 2013. https://doi.org/10.1111/j.1755-3768.2013.F006.x.

Publication types