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. 2021 Feb 25;13(7):874-883.
doi: 10.1039/d1ay00041a.

Detection of the SARS-CoV-2 spike protein in saliva with Shrinky-Dink© electrodes

Julia A Zakashansky  1 , Amanda H Imamura  2 , Darwin F Salgado 2nd  3 , Heather C Romero Mercieca  3 , Raphael F L Aguas  3 , Angelou M Lao  3 , Joseph Pariser  3 , Netzahualcóyotl Arroyo-Currás  4 , Michelle Khine  3
Affiliations

Detection of the SARS-CoV-2 spike protein in saliva with Shrinky-Dink© electrodes

Julia A Zakashansky et al. Anal Methods. .

Abstract

Using the children's toy, Shrinky-Dink©, we present an aptamer-based electrochemical (E-AB) assay that recognizes the spike protein of SARS-CoV-2 in saliva for viral infection detection. The low-cost electrodes are implementable at population scale and demonstrate detection down to 1 ag mL-1 of the S1 subunit of the spike protein.

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