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Review
. 2021 Jul 1;47(7):865-869.
doi: 10.1097/j.jcrs.0000000000000574.

Practice patterns of corneal transplantation in Europe: first report by the European Cornea and Cell Transplantation Registry

Suryan L Dunker  1 , W John Armitage, Margareta Armitage, Lucia Brocato, Francisco C Figueiredo, Martin B A Heemskerk, Jesper Hjortdal, Gary L A Jones, Cynthia Konijn, Rudy M M A Nuijts, Mats Lundström, Mor M Dickman
Affiliations
Review

Practice patterns of corneal transplantation in Europe: first report by the European Cornea and Cell Transplantation Registry

Suryan L Dunker et al. J Cataract Refract Surg. .

Abstract

Purpose: To report practice patterns of corneal transplantation in Europe.

Setting: Corneal clinics in 10 European member states (MS), the United Kingdom, and Switzerland.

Design: Multinational registry study.

Methods: Corneal transplant procedures registered in the European Cornea and Cell Transplantation Registry were identified. Preoperative donor and recipient characteristics, indication and reason for transplantation, and surgical techniques were analyzed.

Results: A total of 12 913 corneal transplants were identified from 10 European Union MS, the United Kingdom, and Switzerland. Most countries were self-sufficient with regard to donor tissue. Fuchs endothelial corneal dystrophy was the most common indication (41%, n = 5325), followed by regraft (16%, n = 2108), pseudophakic bullous keratopathy (12%, n = 1594), and keratoconus (12%, n = 1506). Descemet stripping automated endothelial keratoplasty (DSAEK, 46%, n = 5918) was the most commonly performed technique, followed by penetrating keratoplasty (30%, n = 3886) and Descemet membrane endothelial keratoplasty (9%, n = 1838). Vision improvement was the main reason for corneal transplantation (90%, n = 11 591). Surgical technique and reason for transplantation differed between indications.

Conclusions: This report provides the most comprehensive overview of corneal transplantation practice patterns in Europe to date. Fuchs endothelial dystrophy is the most common indication, vision improvement the leading reason, and DSAEK the predominant technique for corneal transplantation.

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References

    1. Larsson S, Lawyer P, Garellick G, Lindahl B, Lundstrom M. Use of 13 disease registries in 5 countries demonstrates the potential to use outcome data to improve health care's value. Health Aff (Millwood) 2012;31:220–227
    1. Deng SX, Lee WB, Hammersmith KM, Kuo AN, Li JY, Shen JF, Weikert MP, Shtein RM. Descemet membrane endothelial keratoplasty: safety and outcomes: a report by the American Academy of Ophthalmology. Ophthalmology 2018;125:295–310
    1. Lee WB, Jacobs DS, Musch DC, Kaufman SC, Reinhart WJ, Shtein RM. Descemet's stripping endothelial keratoplasty: safety and outcomes: a report by the American Academy of Ophthalmology. Ophthalmology 2009;116:1818–1830
    1. Reinhart WJ, Musch DC, Jacobs DS, Lee WB, Kaufman SC, Shtein RM. Deep anterior lamellar keratoplasty as an alternative to penetrating keratoplasty a report by the American Academy of Ophthalmology. Ophthalmology 2011;118:209–218
    1. Eye Bank Association of America. 2018 eye banking statistical report. Available at: https://restoresight.org/wp-content/uploads/2019/03/2018_Statistical_Rep... . Accessed November 18, 2020

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