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. 2021 Feb 12;11(1):3693.
doi: 10.1038/s41598-021-83263-4.

Trends in osteoporosis and mean bone density among type 2 diabetes patients in the US from 2005 to 2014

Yingke Xu  1   2 , Qing Wu  3   4
Affiliations

Trends in osteoporosis and mean bone density among type 2 diabetes patients in the US from 2005 to 2014

Yingke Xu et al. Sci Rep. .

Abstract

This study aimed to examine how bone health changed among T2DM patients in the past decade. Continuous National Health and Nutrition Examination Survey (NHANES) data from 2005-2006 to 2013-2014 were analyzed to examine the trends of bone mineral density (BMD) and the prevalence trends of osteoporosis osteopenia among T2DM patients and non-diabetic people aged 40 years and older. The age- and BMI-adjusted mean BMD of the femur neck for the four NHANES cycles decreased linearly in both T2DM patients and non-diabetic people (both Plinear trend ≤ 0.009). Among women with T2DM, the mean BMD in 2013-2014 was significantly lower than that in 2005-2006, even after adjusting for multiple covariates. During 2005-2014, the prevalence of osteoporosis among T2DM patients and non-diabetic people increased but with no significant linear trend (both Plinear trend > 0.05), while the prevalence of osteopenia in the two populations increased linearly (both Plinear trend < 0.04). Age- and BMI-adjusted mean BMD decreased in 2013-2014 in patients with T2DM and non-diabetic people, while the prevalence of osteoporosis and osteopenia increased in both groups.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Figure 1
Figure 1
Age and body mass index-adjusted mean bone mineral density in 4 NHANES (2005–2006, 2007–2008, 2009–2010, and 2013–2014).
See this image and copyright information in PMC

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