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. 2021 Jun;48(6):864-875.
doi: 10.1111/1346-8138.15803. Epub 2021 Feb 13.

Epidemiological survey of the psoriasis patients in the Japanese Society for Psoriasis Research from 2013 to 2018

Koji Kamiya  1 , Naoki Oiso  2 , Akira Kawada  2 , Mamitaro Ohtsuki  1
Affiliations

Epidemiological survey of the psoriasis patients in the Japanese Society for Psoriasis Research from 2013 to 2018

Koji Kamiya et al. J Dermatol. 2021 Jun.

Abstract

In Japan, the Japanese Society for Psoriasis Research (JSPR) has been conducting annual epidemiological surveys of patients with psoriasis since 1982. The aim of this study was to conduct a recent epidemiological analysis of the psoriasis patients who were enrolled in the JSPR from 2013 to 2018. A total of 15 287 cases were enrolled from 132 medical institutions, out of which 65.3% (9989 cases) were male and 34.7% (5298 cases) were female. Approximately 50.0% of the cases had past history and comorbidities, such as hypertension (42.0%), dyslipidemia (30.0%), diabetes mellitus (23.7%), hyperuricemia (15.1%), cardiovascular disease (6.0%), and cerebral vascular disorders (6.0%). There was a yearly increase in the use of corticosteroid/vitamin D3 combinations and apremilast for treating psoriasis. In contrast, the use of phototherapy gradually decreased. From 2013 to 2018, approximately 18.6% of the cases were treated with biologics, such as infliximab (17.6%), adalimumab (23.3%), ustekinumab (21.4%), secukinumab (11.6%), ixekizumab (7.6%), brodalumab (6.3%), and guselkumab (4.3%). In the past decade, the biologics have changed the treatment and management of psoriasis. This survey includes significant information regarding the recent perspective of psoriasis in the Japanese Society, especially focusing on the treatment trends after the introduction of biologics.

Keywords: Japan; dermatology; epidemiology; psoriasis; survey.

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Conflict of interest statement

M.O. has received a grant for research and/or honoraria for lectures and/or advisory membership participation from Abbvie, Celgene, Eisai, Eli Lilly, Janssen, LEO Pharma, Maruho, Mitsubishi Tanabe Pharma, Novartis, Taiho Pharmaceutical, and Torii Pharmaceutical.

Figures

FIGURE 1
FIGURE 1
Age and sex distribution
FIGURE 2
FIGURE 2
Age at onset
FIGURE 3
FIGURE 3
Anatomical distribution of the skin lesions at first examination
FIGURE 4
FIGURE 4
Treatment trends in topical therapy
FIGURE 5
FIGURE 5
Treatment trends in phototherapy. BB‐UVB, broadband ultraviolet B; NB‐UVB, narrowband ultraviolet B; PUVA, psoralen and ultraviolet A
FIGURE 6
FIGURE 6
Treatment trends in oral medication. NSAIDs, non‐steroidal anti‐inflammatory drugs
FIGURE 7
FIGURE 7
Treatment trends in the biologics. Secukinumab became available in 2015. Ixekizumab and brodalumab became available in 2016. Biosimilars became available in 2017. Guselkumab became available in 2018
See this image and copyright information in PMC

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