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Review
. 2021 Mar 18;184(6):1621-1635.
doi: 10.1016/j.cell.2021.01.005. Epub 2021 Feb 12.

Genome engineering for crop improvement and future agriculture

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Free article
Review

Genome engineering for crop improvement and future agriculture

Caixia Gao. Cell. .
Free article

Abstract

Feeding the ever-growing population is a major challenge, especially in light of rapidly changing climate conditions. Genome editing is set to revolutionize plant breeding and could help secure the global food supply. Here, I review the development and application of genome editing tools in plants while highlighting newly developed techniques. I describe new plant breeding strategies based on genome editing and discuss their impact on crop production, with an emphasis on recent advancements in genome editing-based plant improvements that could not be achieved by conventional breeding. I also discuss challenges facing genome editing that must be overcome before realizing the full potential of this technology toward future crops and food production.

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Conflict of interest statement

Declaration of interests C. Gao is an advisory board member at Cell.

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