Genome engineering for crop improvement and future agriculture
- PMID: 33581057
- DOI: 10.1016/j.cell.2021.01.005
Genome engineering for crop improvement and future agriculture
Abstract
Feeding the ever-growing population is a major challenge, especially in light of rapidly changing climate conditions. Genome editing is set to revolutionize plant breeding and could help secure the global food supply. Here, I review the development and application of genome editing tools in plants while highlighting newly developed techniques. I describe new plant breeding strategies based on genome editing and discuss their impact on crop production, with an emphasis on recent advancements in genome editing-based plant improvements that could not be achieved by conventional breeding. I also discuss challenges facing genome editing that must be overcome before realizing the full potential of this technology toward future crops and food production.
Copyright © 2021 Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of interests C. Gao is an advisory board member at Cell.
Similar articles
-
Plant genome engineering from lab to field-a Keystone Symposia report.Ann N Y Acad Sci. 2021 Dec;1506(1):35-54. doi: 10.1111/nyas.14675. Epub 2021 Aug 25. Ann N Y Acad Sci. 2021. PMID: 34435370 Review.
-
Current progress and challenges in crop genetic transformation.J Plant Physiol. 2021 Jun;261:153411. doi: 10.1016/j.jplph.2021.153411. Epub 2021 Apr 5. J Plant Physiol. 2021. PMID: 33872932 Review.
-
Genome engineering and plant breeding: impact on trait discovery and development.Plant Cell Rep. 2016 Jul;35(7):1475-86. doi: 10.1007/s00299-016-1993-z. Epub 2016 May 18. Plant Cell Rep. 2016. PMID: 27193593 Free PMC article. Review.
-
Perspectives on the Application of Genome-Editing Technologies in Crop Breeding.Mol Plant. 2019 Aug 5;12(8):1047-1059. doi: 10.1016/j.molp.2019.06.009. Epub 2019 Jun 28. Mol Plant. 2019. PMID: 31260812 Review.
-
New Horizons for Dissecting Epistasis in Crop Quantitative Trait Variation.Annu Rev Genet. 2020 Nov 23;54:287-307. doi: 10.1146/annurev-genet-050720-122916. Epub 2020 Sep 1. Annu Rev Genet. 2020. PMID: 32870731 Review.
Cited by
-
Multiplex CRISPR/Cas9-mediated raffinose synthase gene editing reduces raffinose family oligosaccharides in soybean.Front Plant Sci. 2022 Nov 15;13:1048967. doi: 10.3389/fpls.2022.1048967. eCollection 2022. Front Plant Sci. 2022. PMID: 36457532 Free PMC article.
-
A simple and efficient in planta transformation method based on the active regeneration capacity of plants.Plant Commun. 2024 Apr 8;5(4):100822. doi: 10.1016/j.xplc.2024.100822. Epub 2024 Jan 18. Plant Commun. 2024. PMID: 38243598 Free PMC article.
-
Context effects on repair of 5'-overhang DNA double-strand breaks induced by Cas12a in Arabidopsis.Plant Direct. 2024 Oct 17;8(10):e70009. doi: 10.1002/pld3.70009. eCollection 2024 Oct. Plant Direct. 2024. PMID: 39421463 Free PMC article.
-
Somatic embryogenesis from mature sorghum seeds: An underutilized genome editing recipient system.Heliyon. 2023 Dec 13;10(1):e23638. doi: 10.1016/j.heliyon.2023.e23638. eCollection 2024 Jan 15. Heliyon. 2023. PMID: 38187328 Free PMC article.
-
Knockout of Tobacco Homologs of Arabidopsis Multi-Antibiotic Resistance 1 Gene Confers a Limited Resistance to Aminoglycoside Antibiotics.Int J Mol Sci. 2022 Feb 11;23(4):2006. doi: 10.3390/ijms23042006. Int J Mol Sci. 2022. PMID: 35216118 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources