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Comparative Study
. 1988 Jan;30(1):39-43.

[Morphocytochemical and electron microscopic research on murine hybridoma cells producing and not producing monoclonal antibodies]

[Article in Russian]
  • PMID: 3358281
Comparative Study

[Morphocytochemical and electron microscopic research on murine hybridoma cells producing and not producing monoclonal antibodies]

[Article in Russian]
S P Sidorenko et al. Tsitologiia. 1988 Jan.

Abstract

Cytochemical and ultrastructural features of mouse hybridomas and also of the parental cells--myeloma P3-X63-Ag8.653 and spleen cells of the Balb/c mice immunized with cell line RPMI-1788 have been studied. Differences in cytomorphological signs and activity of acid phosphatase, acid nonspecific esterase, nonspecific-alpha-naphthyl acetate esterase were shown in hybrid cell lines secreting and not secreting monoclonal antibodies.

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