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Review
. 2021 May 21;39(22):3028-3036.
doi: 10.1016/j.vaccine.2021.01.053. Epub 2021 Jan 28.

Acute respiratory distress syndrome (ARDS) as an adverse event following immunization: Case definition & guidelines for data collection, analysis, and presentation of immunization safety data

Nathan A Serazin  1 , Bassey Edem  2 , Sarah R Williams  3 , Justin R Ortiz  4 , Anand Kawade  5 , Manoj Kumar Das  6 , Maja Šubelj  7 , Kathryn M Edwards  8 , Shreemanta K Parida  9 , T Anh Wartel  10 , Flor M Munoz  11 , Patricia Bastero  12
Affiliations
Review

Acute respiratory distress syndrome (ARDS) as an adverse event following immunization: Case definition & guidelines for data collection, analysis, and presentation of immunization safety data

Nathan A Serazin et al. Vaccine. .

Abstract

This is a Brighton Collaboration Case Definition of the term "Acute Respiratory Distress Syndrome - ARDS" to be utilized in the evaluation of adverse events following immunization. The Case Definition was developed by a group of experts convened by the Coalition for Epidemic Preparedness Innovations (CEPI) in the context of active development of vaccines for SARS-CoV-2 vaccines and other emerging pathogens. The case definition format of the Brighton Collaboration was followed to develop a consensus definition and defined levels of certainty, after an exhaustive review of the literature and expert consultation. The document underwent peer review by the Brighton Collaboration Network and by selected Expert Reviewers prior to submission. The comments of the reviewers were taken into consideration and edits incorporated in this final manuscript.

Keywords: ARDS; Acute respiratory distress syndrome; Adult; Adverse event; COVID-19; Case definition; Guidelines; Immunization; Pediatric.

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Conflict of interest statement

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Algorithm for the assessment of ARDS using the Brighton Collaboration Case Definition.
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