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. 2020 Fall;47(3):150-160.

Cancer Incidence in Older Adults in the United States: Characteristics, Specificity, and Completeness of the Data

Hannah K Weir  1 , Recinda Sherman  2 , Mandi Yu  3 , Susan Gershman  4 , Brenda M Hofer  5 , Manxia Wu  1 , Don Green  6
Affiliations

Cancer Incidence in Older Adults in the United States: Characteristics, Specificity, and Completeness of the Data

Hannah K Weir et al. J Registry Manag. 2020 Fall.

Abstract

Introduction: The number of cancer cases in the United States continues to grow as the number of older adults increases. Accurate, reliable and detailed incidence data are needed to respond effectively to the growing human costs of cancer in an aging population. The purpose of this study was to examine the characteristics of incident cases and evaluate the impact of death-certificate-only (DCO) cases on cancer incidence rates in older adults.

Methods: Using data from 47 cancer registries and detailed population estimates from the Surveillance, Epidemiology and End Results (SEER) Program, we examined reporting sources, methods of diagnosis, tumor characteristics, and calculated age-specific incidence rates with and without DCO cases in adults aged 65 through ≥95 years, diagnosed 2011 through 2015, by sex and race/ethnicity.

Results: The percentage of cases (all cancers combined) reported from a hospital decreased from 90.6% (ages 65-69 years) to 69.1% (ages ≥95 years) while the percentage of DCO cases increased from 1.1% to 19.6%. Excluding DCO cases, positive diagnostic confirmation decreased as age increased from 96.8% (ages 65-69 years) to 69.2% (ages ≥95 years). Compared to incidence rates that included DCO cases, rates in adults aged ≥95 years that excluded DCO cases were 41.5% lower in Black men with prostate cancer and 29.2% lower in Hispanic women with lung cancer.

Discussion: Loss of reported tumor specificity with age is consistent with fewer hospital reports. However, the majority of cancers diagnosed in older patients, including those aged ≥95 years, were positively confirmed and were reported with known site, histology, and stage information. The high percentage of DCO cases among patients aged ≥85 years suggests the need to explore additional sources of follow-back to help possibly identify an earlier incidence report. Interstate data exchange following National Death Index linkages may help registries identify and remove erroneous DCO cases from their databases.

Keywords: Cancer in North America (CiNA); National Program of Cancer Registries; North American Association of Central Cancer Registries; Surveillance, Epidemiology, and End Results Program; cancer incidence; cancer registries; case ascertainment; death certificate only; interstate data exchange; older adults.

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Figures

Figure 1.
Figure 1.. Percentage of Incident Cases Ascertained from Death Certicates Only for All Cancer Cases Combined by Sex, Race/Ethnicity, and Age among Adults Aged ≥65 Years (2011–2015)
Figure 2.
Figure 2.. Distribution of Cancer Types among Adults Aged ≥85 Years by Sex, Race/Ethnicity, and Age Group (2011–2015)
Selected cancers were those with a minimum 5% of cases in 2 or more of the 3 age groups (85–89 years, 90–94 years, ≥95 years).
Figure 3.
Figure 3.
Age-Specific Incidence Rates for Selected Cancers among Adults Aged ≥65 Years, With and Without Death-Certificate-Only Cases, by Sex and Race/Ethnicity (2011–2015)
See this image and copyright information in PMC

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