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Multicenter Study
. 2021 Aug;40(8):1737-1742.
doi: 10.1007/s10096-020-04140-y. Epub 2021 Feb 14.

Changes in antimicrobial resistance and outcomes of health care-associated infections

Mehtap Aydın  1 , Emel Azak  2 , Hüseyin Bilgin  3 , Sirin Menekse  4 , Ali Asan  5 , Habibe Tülin Elmaslar Mert  6 , Zerrin Yulugkural  6 , Lutfiye Nilsun Altunal  7 , Çiğdem Ataman Hatipoğlu  8 , Gunay Tuncer Ertem  8 , Elif Sargın Altunok  9 , Melike Hamiyet Demirkaya  10 , Sevil Alkan Çeviker  11 , Fethiye Akgul  12 , Zeynep Memis  13 , Petek Konya  14 , Alpay Azap  15 , Gule Aydin  15 , Derya Korkmaz  16 , Zehra Çagla Karakoç  17 , Derya Yapar  18 , Faruk Karakecili  19 , Ozgur Gunal  20 , Siran Keske  21 , Mahir Kapmaz  21 , Cigdem Kader  22 , Aslıhan Demirel  23 , Önder Ergönül  21
Affiliations
Multicenter Study

Changes in antimicrobial resistance and outcomes of health care-associated infections

Mehtap Aydın et al. Eur J Clin Microbiol Infect Dis. 2021 Aug.

Abstract

To describe the change in the epidemiology of health care-associated infections (HAI), resistance and predictors of fatality we conducted a nationwide study in 24 hospitals between 2015 and 2018. The 30-day fatality rate was 22% in 2015 and increased to 25% in 2018. In BSI, a significant increasing trend was observed for Candida and Enterococcus. The highest rate of 30-day fatality was detected among the patients with pneumonia (32%). In pneumonia, Pseudomonas infections increased in 2018. Colistin resistance increased and significantly associated with 30-day fatality in Pseudomonas infections. Among S. aureus methicillin, resistance increased from 31 to 41%.

Keywords: Blood stream infections; Colistin resistance; Health care; associated infections.

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References

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