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Review
. 2021 Apr;44(8):1592-1611.
doi: 10.1002/jssc.202100017. Epub 2021 Mar 19.

Comprehensive two-dimensional gas chromatography as a boosting technology in food-omic investigations

Federico Stilo  1 , Carlo Bicchi  1 , Stephen E Reichenbach  2   3 , Chiara Cordero  1
Affiliations
Review

Comprehensive two-dimensional gas chromatography as a boosting technology in food-omic investigations

Federico Stilo et al. J Sep Sci. 2021 Apr.

Abstract

This review focuses on the role that comprehensive two-dimensional gas chromatography can play within the investigation workflows of food-omics and related disciplines and subdisciplines, including food metabolomics, nutrimetabolomics, sensomics, and food safety. After a short introductory survey, discussing the intriguing context of system biology and integrationist approaches of investigation, the concepts of analytical dimensions and the key characteristics of comprehensive two-dimensional gas chromatography are introduced. Through a selection of relevant examples, the boosting role of comprehensive two-dimensional gas chromatography within food-omics is described, providing to the reader evidence of how comprehensive multidimensional separations based platforms have introduced new concepts and tools in the analytical measurement of complex biological samples.

Keywords: comprehensive two-dimensional gas chromatography; food metabolomics; food safety; nutrimetabolomics; sensomics.

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References

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