Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Feb;14(1):60-66.
doi: 10.1007/s12178-020-09685-1. Epub 2021 Feb 15.

Surgical Management of Osteochondral Defects of the Knee: An Educational Review

Affiliations
Review

Surgical Management of Osteochondral Defects of the Knee: An Educational Review

Matthew Howell et al. Curr Rev Musculoskelet Med. 2021 Feb.

Abstract

Purpose of review: Numerous surgical techniques are available to treat osteochondral defects of the knee. The aim of this review is to analyse these procedures, including their methodology, outcomes and limitations, to create a treatment algorithm for optimal management.

Recent findings: Osteochondral defects of the knee significantly alter the biomechanics of the joint. This can cause symptomatic and functional impairment as well as considerable risk of progressive joint degeneration. Surgical interventions aim to restore a congruent, durable joint surface providing symptomatic relief and reducing the risk of early arthritic changes. These methods include fixation, chondroplasty, microfracture, autologous matrix-induced chondrogenesis, autograft transplants, allograft transplants and autologous chondrocyte implantation. There is currently much debate as to which of these methods provides optimal treatment of osteochondral defects. The overall evidence supports the use of each technique depending on the individual characteristics of the lesion. New technologies provide exciting prospects; however, long-term outcomes for these are not yet available.

Keywords: Autograft; Autologous; Cartilage; Knee; Osteochondral; Osteochondritis dissecans.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Illustration comparing OATS and mosaicplasty procedures
Fig. 2
Fig. 2
Illustration demonstrating autologous chondrocyte implantation (ACI) procedure
Fig. 3
Fig. 3
Treatment algorithm for osteochondral defects of the knee

References

    1. Grimm NL, Weiss JM, Kessler JI, Aoki SK. Osteochondritis dissecans of the knee: pathoanatomy, epidemiology, and diagnosis. Clin Sports Med. 2014;33(2):181–188. - PubMed
    1. Heir S, Nerhus TK, Røtterud JH, Løken S, Ekeland A, Engebretsen L, Arøen A. Focal cartilage defects in the knee impair quality of life as much as severe osteoarthritis: a comparison of knee injury and osteoarthritis outcome score in 4 patient categories scheduled for knee surgery. Am J Sports Med. 2010;382:231–237. - PubMed
    1. Craig W, David JW, Ming HZ. A current review on the biology and treatment of the articular cartilage defects [part I & part II] J Musculoskelet Res. 2003;7:157–181.
    1. Bohndorf K. Osteochondritis [osteochondrosis] dissecans a review and new MRI classification. Eur Radiol. 1998;8:103–112. - PubMed
    1. Sanders TL, Pareek A, Obey MR, Johnson NR, Carey JL, Stuart MJ, Krych AJ. High rate of osteoarthritis after osteochondritis dissecans fragment excision compared with surgical restoration at a mean 16-year follow-up. Am J Sports Med. 2017;45:1799–1805. - PubMed

LinkOut - more resources