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Case Reports
. 2021 Jul;35(7):e411-e412.
doi: 10.1111/jdv.17170. Epub 2021 Mar 20.

Rapidly progressive alopecia areata totalis in a COVID-19 patient, unresponsive to tofacitinib

S Berbert Ferreira  1   2 , M F R Gavazzoni Dias  3 , R Berbert Ferreira  2   4 , A C Neves Neto  4 , R M Trüeb  5   6 , O Lupi  7   8
Affiliations
Case Reports

Rapidly progressive alopecia areata totalis in a COVID-19 patient, unresponsive to tofacitinib

S Berbert Ferreira et al. J Eur Acad Dermatol Venereol. 2021 Jul.
No abstract available

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Conflict of interest statement

The authors have no conflict of interest to declare.

Figures

Figure 1
Figure 1
Patient, before the pandemic, with a full‐grown hair and no signs of disease activity, using tofacitinib 5 mg BID.
Figure 2
Figure 2
Active alopecia areata 90 days after reintroduction of tofacitinib 5 mg BID. Dermoscopy shows exclamation mark hairs, black and yellow dots.
See this image and copyright information in PMC

References

    1. Trüeb RM, Dias MFRG. Alopecia areata: a comprehensive review of pathogenesis and management. Clin Rev Allergy Immunol 2018; 54: 68–87. - PubMed
    1. Berbert Ferreira R, Ferreira SB, Scheinberg MA. An excellent response to tofacitinib in a Brazilian adolescent patient with alopecia areata: a case report and a review of the literature. Clin Case Rep 2019; 7: 2539–2542. - PMC - PubMed
    1. Craiglow BG, King BA. Killing two birds with one stone: oral tofacitinib reverses alopecia universalis in a patient with plaque psoriasis. J Invest Dermatol 2014; 134: 2988–2990. - PubMed
    1. Spinelli FR, Immunol S, Spinelli FR et al. HiJAKing SARS‐CoV‐2? The potential role of JAK inhibitors in the management of COVID‐19. Sci Immunol 2020; 5367: 1–6. - PubMed
    1. Schmidt ME, Varga SM. The CD8 T cell response to respiratory virus infections. Front Immunol 2018; 9: 6–9. - PMC - PubMed

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