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Case Reports
. 2021 Mar-Apr;96(2):234-236.
doi: 10.1016/j.abd.2020.06.011. Epub 2021 Feb 2.

Case for diagnosis. Atypical Grover's disease

Affiliations
Case Reports

Case for diagnosis. Atypical Grover's disease

Pablo Vargas-Mora et al. An Bras Dermatol. 2021 Mar-Apr.

Abstract

A 55-year-old male presented with an eight-month history of erythematous papules and plaques with demarcated areas of spared skin on his trunk, upper extremities, neck, and face. Grover's disease is a rare, acquired disorder of unknown origin, which is classically characterized by the appearance of erythematous papules on the upper trunk that are usually transient. As in the present case, there are reports of atypical disease, with facial involvement, pityriasis rubra pilaris-like lesions, and a more chronic course.

Keywords: Acantholysis; Atypical; Grover’s disease; Transient acantholytic dermatosis.

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Figures

Figure 1
Figure 1
(A and B) Erythematous papules and plaques with well-demarcated areas of spared skin on anterior thorax and back.
Figure 2
Figure 2
(A and B) Erythematous papules and plaques with superficial scaling on the face.
Figure 3
Figure 3
Dermoscopy shows a pink background with dotted and glomerular vessels, and fine white scaling.
Figure 4
Figure 4
(A and B) Suprabasal acantholysis with focal spongiosis and numerous dyskeratotic cells (Hematoxylin & eosin, ×40 and ×100, respectively).

References

    1. Aldana P.C., Khachemoune A. Grover disease: review of subtypes with a focus on management options. Int J Dermatol. 2020;59:543–550. - PubMed
    1. Quirk C.J., Heenan P.J. Grover’s disease: 34 years on. Australas J Dermatol. 2004;45:83–88. - PubMed
    1. Weaver J., Bergfeld W.F. Grover disease (transient acantholytic dermatosis) Arch Pathol Lab Med. 2009;133:1490–1494. - PubMed
    1. Motaparthi K. Pseudoherpetic transient acantholytic dermatosis (Grover disease): case series and review of the literature. J Cutan Pathol. 2017;44:486–489. - PubMed
    1. Arceu M., Martinez G., Arellano J., Corredoira Y., Frenkel C. Caracterización de pacientes con diagnóstico de enfermedad de Hailey-Hailey, enfermedad de Darier y enfermedad de Grover, entre los años 2007 y 2017 en el Hospital Clínico San Borja Arriaran y revisión de la literatura. Rev Chil Dermatol. 2019;35:36–43.

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