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. 2021 Jun;41(6):1236-1243.
doi: 10.1038/s41372-021-00952-8. Epub 2021 Feb 15.

Outcomes of mothers and newborns to prenatal exposure to kratom: a systematic review

Mary Ellen Wright  1 , Claire Ginsberg  2 , Abigail M Parkison  2 , Melissa Dubose  2 , Madison Sherbondy  2 , Emily Shores  2   3
Affiliations

Outcomes of mothers and newborns to prenatal exposure to kratom: a systematic review

Mary Ellen Wright et al. J Perinatol. 2021 Jun.

Erratum in

Abstract

Kratom is a legal, widely available substance that contains opioid agonist alkaloids. Due to the marketing of kratom as an opioid alternative for treatment of pain, anxiety, depression, or to reduce opioid withdrawal symptoms, the use of kratom has increased among persons in the USA including pregnant women. This systematic review of the peer-reviewed literature regarding kratom in relation to maternal and infant outcomes resulted in analysis of six case reports of prenatal kratom exposure. Maternal and infant withdrawal from kratom exposure was described in each case, resulting in pharmacologic treatment for both mothers and infants.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1. Prisma flow diagram.
Databases used: PubMed, CINAHL, Cochrane Review Google scholar, and EBSCOhost. Key search terms: “Kratom and neonatal abstinence syndrome,” “Kratom and neonatal effects,” and “Kratom and pregnancy”.
See this image and copyright information in PMC

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