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Clinical Trial
. 1977 Dec;134(12):1408-10.
doi: 10.1176/ajp.134.12.1408.

The treatment of perceptual disturbances in schizophrenia with naloxone hydrochloride

A A Kurland, O L McCabe, T E Hanlon, D Sullivan
Clinical Trial

The treatment of perceptual disturbances in schizophrenia with naloxone hydrochloride

A A Kurland et al. Am J Psychiatry. 1977 Dec.

Abstract

The authors treated 12 schizophrenic patients who had overt hallucinatory symptoms with intravenously administered naloxone hydrochloride, a narcotic antagonist purported to have antihallucinatory properties. They found no evidence of the effectiveness of naloxone in preventing hallucinations over that of placebo when administered in a randomized, double-blind fashion.

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