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. 2021 Apr;32(4):925-930.
doi: 10.1111/jce.14951. Epub 2021 Mar 4.

First experience of POLARx™ versus Arctic Front Advance™: An early technology comparison

Antonio Creta  1 , Viijayabharathy Kanthasamy  1 , Richard J Schilling  1 , James Rosengarten  1 , Fakhar Khan  1 , Shohreh Honarbakhsh  1 , Mark J Earley  1 , Ross J Hunter  1 , Malcom Finlay  1
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First experience of POLARx™ versus Arctic Front Advance™: An early technology comparison

Antonio Creta et al. J Cardiovasc Electrophysiol. 2021 Apr.

Abstract

Introduction: Cryoballoon ablation is an established technique to achieve pulmonary vein isolation in patients with atrial fibrillation (AF). Recently, a new manufacturer of cryoballoon achieved regulatory CE marking (POLARx™; Boston Scientific). We describe our early experience of using this new market entrant of the technology and describe procedural aspects in comparison to the incumbent Medtronic Arctic Front Advance™.

Methods: We assessed the first 40 AF ablations performed with the POLARx catheter at the Barts Heart Centre. These patients were compared with a contemporaneous series of patients undergoing ablation by the same operators using the Arctic Front Advance. Procedural metrics were prospectively recorded.

Results: A total of four operators undertook 40 cases using the POLARx catheter, compared with 40 cases using the Arctic Front Advance. Procedure times (60.0 vs. 60.0 min) were similar between the two technologies, however left atrial dwell time (35.0 vs 39.0 min) and fluoroscopy times (3.3 vs. 5.2 min) were higher with the POLARx. Measured nadir and isolation balloon temperatures were significantly lower with POLARx. Almost all veins were isolated with a median freezing time of 16.0 (POLARx) versus 15.0 (Arctic Front Advance) min. The rate of procedural complications was low in both groups.

Conclusion: The POLARx cryoballoon is effective for pulmonary vein isolation. Measured isolation and nadir temperatures are lower compared with the predicate Arctic Front Advance catheter. The technology appears similar in acute efficacy and has a short learning curve, but formal dosing studies may be required to prove equivalence of efficacy.

Keywords: atrial fibrillation; catheter ablation; cryoballoon; technology.

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References

REFERENCES

    1. Asad ZUA, Yousif A, Khan MS, Al-Khatib SM, Stavrakis S. Catheter ablation versus medical therapy for atrial fibrillation: a systematic review and meta-analysis of randomized controlled trails. Circ Arrhythm Electrophysiol. 2019;12(9):e007414.
    1. Calkins H, Hindricks G, Cappato R, et al. 2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation. Heart Rhythm. 2017;14:e275-e444.
    1. Kuck KH, Brugada J, FIRE AND ICE Investigators, et al. Cryoballoon or radiofrequency ablation for paroxysmal atrial fibrillation. N Engl J Med. 2016;374:2235-2245.
    1. Boveda S, Metzner A, Nguyen DQ, et al. Single-procedure outcomes and quality-of-life improvement 12 months post-cryoballoon ablation in persistent atrial fibrillation: results from the multicenter CRYO4PERSISTENT AF trial. JACC Clin Electrophysiol. 2018;4(11):1440-1447.
    1. Su WW, Reddy VY, STOP Persistent AF Investigators, et al. Cryoballoon ablation of pulmonary veins for persistent atrial fibrillation: Results from the multicenter STOP Persistent AF trial. Heart Rhythm. 2020;17(20):1841-1847.

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