A review on current diagnostic techniques for COVID-19

Islam El Jaddaoui¹, Malika Allali^{1

2}, Sanae Raoui¹, Sofia Sehli³, Nihal Habib³, Bouchra Chaouni⁴, Najib Al Idrissi⁵, Najwa Benslima⁶, Wissal Maher⁷, Houda Benrahma³, Noureddine Hamamouch⁴, Kamal El Bissati⁸, Sahar El Kasmi⁹, Salsabil Hamdi², Youssef Bakri¹, Chakib Nejjari^{10

11}, Saaïd Amzazi¹, Hassan Ghazal^{3

12}

Affiliations

¹ Laboratory of Human Pathologies Biology, Department of Biology, Faculty of Sciences, and Genomic Center of Human Pathologies, Faculty of Medicine and Pharmacy, University Mohammed V, Rabat, Morocco.
² Environmental Health Laboratory, Department of Research, Institut Pasteur Maroc, Casablanca, Morocco.
³ Department of Fundamental Sciences, Faculty of Medicine, Mohammed VI University of Health Sciences (UM6SS), Casablanca, Morocco.
⁴ , Laboratory of Biotechnology and Plant Physiology, Center of Plant and Microbial Biotechnology, Biodiversity and Environment, Department of Biology, Faculty of Sciences, University Mohammed V, Rabat, Morocco.
⁵ , Department of Surgery, Faculty of Medicine, Mohammed VI University of Health Sciences (UM6SS), Casablanca, Morocco.
⁶ Department of Radiology, Faculty of Medicine, Mohammed VI University of Health Sciences (UM6SS), Casablanca, Morocco.
⁷ Research Center, Abulcasis University of Health Sciences, Rabat, Morocco.
⁸ Coalition Center for Innovation and Prevention of Epidemies in Morocco (CIPEM), Mohammed VI Polytechnical University (UM6P), Ben Guerir, Morocco.
⁹ Faculty of Scineces, University Mohammed V, Rabat, Morocco.
¹⁰ Department of Epidemiology and Biostatistics, International School of Public Health, Mohammed VI University of Health Sciences (UM6SS), Casablanca, Morocco.
¹¹ Department of Epidemiology and Public Health, Faculty of Medicine, University Sidi Mohammed Ben Abdellah, Fez, Morocco.
¹² Scientific Department, National Center for Scientific and Technical Research (CNRST),Rabat, Morocco.

PMID: 33593219
DOI: 10.1080/14737159.2021.1886927

Review

A review on current diagnostic techniques for COVID-19

Islam El Jaddaoui et al. Expert Rev Mol Diagn. 2021 Feb.

. 2021 Feb;21(2):141-160.

doi: 10.1080/14737159.2021.1886927. Epub 2021 Mar 18.

Authors

Affiliations

¹ Laboratory of Human Pathologies Biology, Department of Biology, Faculty of Sciences, and Genomic Center of Human Pathologies, Faculty of Medicine and Pharmacy, University Mohammed V, Rabat, Morocco.
² Environmental Health Laboratory, Department of Research, Institut Pasteur Maroc, Casablanca, Morocco.
³ Department of Fundamental Sciences, Faculty of Medicine, Mohammed VI University of Health Sciences (UM6SS), Casablanca, Morocco.
⁴ , Laboratory of Biotechnology and Plant Physiology, Center of Plant and Microbial Biotechnology, Biodiversity and Environment, Department of Biology, Faculty of Sciences, University Mohammed V, Rabat, Morocco.
⁵ , Department of Surgery, Faculty of Medicine, Mohammed VI University of Health Sciences (UM6SS), Casablanca, Morocco.
⁶ Department of Radiology, Faculty of Medicine, Mohammed VI University of Health Sciences (UM6SS), Casablanca, Morocco.
⁷ Research Center, Abulcasis University of Health Sciences, Rabat, Morocco.
⁸ Coalition Center for Innovation and Prevention of Epidemies in Morocco (CIPEM), Mohammed VI Polytechnical University (UM6P), Ben Guerir, Morocco.
⁹ Faculty of Scineces, University Mohammed V, Rabat, Morocco.
¹⁰ Department of Epidemiology and Biostatistics, International School of Public Health, Mohammed VI University of Health Sciences (UM6SS), Casablanca, Morocco.
¹¹ Department of Epidemiology and Public Health, Faculty of Medicine, University Sidi Mohammed Ben Abdellah, Fez, Morocco.
¹² Scientific Department, National Center for Scientific and Technical Research (CNRST),Rabat, Morocco.

PMID: 33593219
DOI: 10.1080/14737159.2021.1886927

Abstract

Introduction: SARS-Cov-2 first appeared in Wuhan, China, in December 2019 and spread all over the world soon after that. Given the infectious nature ofSARS-CoV-2, fast and accurate diagnosis tools are important to detect the virus. In this review, we discuss the different diagnostic tests that are currently being implemented in laboratories and provide a description of various COVID-19 kits.

Areas covered: We summarize molecular techniques that target the viral load, serological methods used for SARS-CoV-2 specific antibodies detection as well as newly developed faster assays for the detection of SARS-COV 2 in various biological samples.

Expert opinion: In the light of the widespread pandemic, the massive diagnosis of COVID-19, using various detection techniques, appears to be the most effective strategy for monitoring and containing its propagation.

Keywords: SARS-COV-2; diagnostic; kits; molecular techniques; serological methods.

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A review on current diagnostic techniques for COVID-19

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A review on current diagnostic techniques for COVID-19

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