doi: 10.1016/0304-3835(88)90102-4.
Ultrastructural localization of cisplatin in Ehrlich ascites tumor cells
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- PMID: 3359413
- DOI: 10.1016/0304-3835(88)90102-4
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Ultrastructural localization of cisplatin in Ehrlich ascites tumor cells
Cancer Lett.
1988 Mar.
Abstract
The incorporation of cis-diammine Dichloro Platinum (II) (cisplatin) on the Ehrlich ascites carcinoma (EAT) cells has been studied in this paper. Ultrastructural study of cells treated 'in vivo' with cisplatin showed that a new treatment with this substance after fixation, blocks uranyl acetate staining with the consequent lack of heterochromatin contrast.
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